Comment 26 for bug 449855

To make sound work with skype and ekiga deactivating pulseaudio did the job for me.

https://wiki.ubuntu.com/PulseAudio for how to disable it
http://pastebin.com/f2e3141cd for a ~/.asoundrc optimized for eee 1005 ha (mixes input down so the mic isn't on one channel only, equalizes sound output so it sound's better with the internal speaker)

Now /all/ of my sound applications work great. I guess this isn't a good idea unless you've got a bit of experience though... :-)