Comment 31 for bug 1014240

I had the same problem on my new laptop (Clevo P650RA), and adding 'i8042.reset' to GRUB_CMDLINE_LINUX_DEFAULT fixed it for me. Shouldn't this be enabled by default?

This is on "Ubuntu Xenial Xerus (development branch) - Release: 16.04" by the way.

My exact kernel error was:

i8042: failed to resume active multiplexor, mouse won't work

In that case, the mouse indeed didn't work, but neither did the touchpad. Closing the laptop lid, waiting for a couple of seconds for it to suspend again and reopening the laptop lid was a workaround to resolve the situation, but the i8042.reset takes away the need to do so.