ruby-crb-blast 0.6.9-1 (i386 binary) in ubuntu bionic
CRB-BLAST is a novel method for finding orthologs between one set of sequences
and another. This is particularly useful in genome and transcriptome
annotation.
.
CRB-BLAST initially performs a standard reciprocal best BLAST. It does this by
performing BLAST alignments of query->target and target->query. Reciprocal
best BLAST hits are those where the best match for any given query sequence in
the query->target alignment is also the best hit of the match in the reverse
(target->query) alignment.
.
Reciprocal best BLAST is a very conservative way to assign orthologs. The main
innovation in CRB-BLAST is to learn an appropriate e-value cutoff to apply to
each pairwise alignment by taking into account the overall relatedness of the
two datasets being compared. This is done by fitting a function to the
distribution of alignment e-values over sequence lengths. The function
provides the e-value cutoff for a sequence of given length.
Details
- Package version:
- 0.6.9-1
- Status:
- Published
- Component:
- universe
- Priority:
- Optional
Downloadable files
- ruby-crb-blast_0.6.9-1_all.deb (11.3 KiB)