Comment 5 for bug 502375

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iltony (iltony) wrote : Re: Wine randomly cannot initialize sound

have you tried the command
pasuspender -- winecfg
?
You can start a program by issuing
pasuspender -- wine .wine/drive_c/Programmi/Macromedia/Flash\ 8/Flash.exe
It suspends pulseaudio for a while and lets you use wine without the hassles it brings.