Comment 8 for bug 421218

I had what may be a similar problem, but found a solution: in winecfg, I noticed that the esd driver option only appeared if pulseaudio was running. So I set the output to go to esd in winecfg. The "test" button in winecfg still failed, but sound worked for me in Steam (TF2 specifically) under Wine. I upgraded to karmic today, and things broke, so I cleared out all of my old pulse settings before doing this, which may have had some effect, but try using esd for winecfg despite the test failure message.