Comment 2 for bug 888497

The culprit is likely to be encrypted home directory rather than transmission.

It looks like kernel and/or ecryptfs and/or ext4 bug.

The fact that file is larger than 4GB appears to be important.

See related bug #913787

My distro LinuxMint 12 (derived from Ubuntu 11.10).

uname -a
Linux saz 3.0.0-12-generic #20-Ubuntu SMP Fri Oct 7 14:50:42 UTC 2011 i686 i686 i386 GNU/Linux

Cheers,
--Sampo