Comment 2 for bug 669142

I experienced the same issue.
I've modified the beginning of the script this way :

PATH=/sbin:/bin:/usr/sbin:/usr/bin
DAEMON=/sbin/iscsid
ADM=/sbin/iscsiadm
PIDFILE=/var/run/iscsid.pid
NAMEFILE=/etc/iscsi/initiatorname.iscsi
ISCSI_INTERFACE="br1:0"

[ -x "$DAEMON" ] || exit 0

# Support for ifupdown script.
# Don't bother to restart when lo is configured.
if [ "$IFACE" != "$ISCSI_INTERFACE" ]; then
        exit 0
fi

So now, appart from the explicitely interface specified, the open-iscsi daemon doesn't restart :)
Pay attention if you use some aliased interfaces though, you coud physically loose the connectivity.