Comment 676 for bug 1690085

I ran into similar problems to this with a Threadripper 1950X and none of the proposed workarounds did anything. Disabling C6 in the BIOS made it fail to boot for some reason. Setting "Typical Current Idle" in the BIOS, processor.max_cstate=1 in the kernel command line, or disabling C6 with ZenStates.py all had no effect. I also tried overclocking and underclocking.

I eventually did a from-scratch reinstall of Fedora 29 and it suddenly just works (for 10+ hours, I don't leave my machine on overnight). Once it started working, I set everything back to the defaults except for "Typical Current Idle" (since I have a PSU from 2010 and I doubt it supports any fancy features from 2013).

Unfortunately I can't easily narrow down all of the changes after the re-install, but the ones I'm aware of are:

 - Using the Nouvea driver (previously proprietary nVidia drivers)
 - Booting in EFI mode now (previously legacy mode)
 - Using ext4 (previously btrfs)

I strongly suspect that the graphics driver was the problem since my lockups would cause the screen to become completely unresponsive, but sound continued working, and in one case I had a lockup during a video call and the other person could still see and hear me.

I plan to try the proprietary drivers again sometime and I'll make a note if that brings the problem back for me.