On a couple of different Jammy VMs, I've seen the system get into the state where only the first searched app is highlighted. Any arrow key strokes move to the panel and do not move back to the list of searched applications. (see video)
1. Press super key to expand the Activities view
2. Start typing something, "software" for example, and see the searched apps narrow
3. The first highlighted app is not what I want. Instead I press the right arrow key to navigate to the second one.
4. As soon as I press the right arrow key, the only running app (terminal) is highlighted in the view. Any left arrow key strokes do not go back to highlighting the first app appearing in the search.
Note that mouse clicks do not work to start the app I want either. I need to Esc or Super to exit the Activities view, relaunch, and make sure my search terms are exact to ensure the first highlighted app is the one I want. Then when I press Enter, the app starts.
Worth noting too that once a VM gets in this state, there's no going back. It's like this 100% of the time, persistent across reboots.