I experiment the same problem: mouse click don't work on gnome-shell after upgrade of ubuntu 16.04 with a NVIDIA card on two different Dell E6410. Sometime inside à windows opened (firefox) it still possible to click on inner elements but not in windows frame buttons. This problems not occurs on unity.
I experiment the same problem: mouse click don't work on gnome-shell after upgrade of ubuntu 16.04 with a NVIDIA card on two different Dell E6410. Sometime inside à windows opened (firefox) it still possible to click on inner elements but not in windows frame buttons. This problems not occurs on unity.