Comment 62 for bug 938751

Ubuntu 21.10
The issue still remain.

In colour setting window, the "remove" button is now disabled.

There is what fixed the issue for me:

Deny any access to any user to the folder contains the ICC files.

$ sudo chmod 000 ~/.local/share/icc
$ reboot

Here is how a track down the ICC folder in use:

1. Install gnome-color-manager
2. Open colour settings.
3. Click the colour profile in use and click the "View profile" button.
4. Find the path to the ICC file.
5. Deny any access to any user to the folder contains the ICC files.