Comment 125 for bug 345627

Sorry, slight correction to my previous post. With kernel 2.6.31-1-generic and glitch-free PulseAudio, Skype does have the problem of hundreds of connections opening/closing - but there is absolutely no stuttering even under CPU load.

This issue is probably due to Skype's buggy implemention of the ALSA API; nevertheless, it just shows that glitch-free handles this problem more robustly than using custom fragment values and lower-quality resamplers (as long as your ALSA kernel driver works correctly).