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1b1ed1a
(Get the code!)
Happens to me sometimes when powering on from suspend -- any USB device plugged in will get the following:
usb 5-1: new full-speed USB device number 21 using uhci_hcd
usb 5-1: device descriptor read/64, error -110
No plugged-in USB device will be properly detected until a cold boot -- camera, mouse, keyboard or harddrive. This is Ubuntus 12.10 through 13.10; may be a hardware problem, but again: it only happens to me after the computer has been in Suspend power mode, and not every time.