Comment 1 for bug 443209

> Changing fonts of part of a sentence to "URW Palladio L" gives
> Palladio, but only bold.

The font "URW Palladio L" has the styles 'Medium' and 'Bold' listed in the 'Text and Font' dialog (as well as the italic variants of both).

In parts reproduced with Inkscape 0.47 on OS X 10.5.8: In inkscape 0.47 the font "URW Palladio L" initially is always set to bold, but unboldening it with the button on the tool controls bar works (the .

Not reproduced with Inkscape 0.48 and 0.48+devel r9873 on OS X 10.5.8: Additional weights have been added in r9332:
<http://bazaar.launchpad.net/~inkscape.dev/inkscape/trunk/revision/9332>

Do you still have the problem to select 'Medium' as font weight with Inkscape 0.48 or a recent development build?