Comment 6 for bug 1188211

I have the same problem on the Microsoft Surface Pro 8 with a 4K monitor attached. The external monitor is on top of the other.

Display 1 (built-in): 2880x1920 at 200% scale
Display 2 (external, on top): 3840x2160 at 125% scale

The pen offset is not constant, the lower it is on my screen the more offset it becomes.

This makes Inkscape unusable. Let me know if I can provide more info.