does this also happen if you use the gui to select an svg file and do a right mouse click on it and select "Open With ... Inkscape"?
It might also be worthwhile to see if there are any unusual references to I: drive in the registry, for example at the locations
HKEY_CLASSES_ROOT\Applications\inkscape.exe\shell\open\command
HKEY_CURRENT_USER\Software\Classes\Applications\inkscape.exe\shell\open\command
does this also happen if you use the gui to select an svg file and do a right mouse click on it and select "Open With ... Inkscape"?
It might also be worthwhile to see if there are any unusual references to I: drive in the registry, for example at the locations
HKEY_CLASSES_ ROOT\Applicatio ns\inkscape. exe\shell\ open\command
HKEY_CURRENT_ USER\Software\ Classes\ Applications\ inkscape. exe\shell\ open\command