Index: src/zope/testing/testrunner.py
===================================================================
--- src/zope/testing/testrunner.py	(revision 81407)
+++ src/zope/testing/testrunner.py	(working copy)
@@ -39,6 +39,8 @@
 import unittest
 
 
+before_tests_hooks = []
+after_tests_hooks = []
 available_profilers = {}
 
 try:
@@ -925,7 +927,8 @@
         # set up the output file
         oshandle, file_path = tempfile.mkstemp(prof_suffix, prof_prefix, '.')
         profiler = available_profilers[options.profile](file_path)
-        profiler.enable()
+        before_tests_hooks.append(profiler.enable)
+        after_tests_hooks.append(profiler.disable)
 
     try:
         try:
@@ -936,7 +939,6 @@
         if tracer:
             tracer.stop()
         if options.profile:
-            profiler.disable()
             profiler.finish()
             # We must explicitly close the handle mkstemp returned, else on
             # Windows this dies the next time around just above due to an
@@ -1259,7 +1261,10 @@
         errors.append((SetUpLayerFailure(), sys.exc_info()))
         return 0
     else:
-        return run_tests(options, tests, layer_name, failures, errors)
+        [hook() for hook in before_tests_hooks]
+        results = run_tests(options, tests, layer_name, failures, errors)
+        [hook() for hook in after_tests_hooks]
+        return results
 
 class SetUpLayerFailure(unittest.TestCase):
     def runTest(self):