--- setup.py
+++ setup.py
@@ -19,7 +19,7 @@
 """Setup for zope.interface package
 """
 
-import os, sys
+import os, platform, sys
 
 try:
     from setuptools import setup, Extension, Feature
@@ -49,6 +49,10 @@
                                              '_zope_interface_coptimizations.c')
                                              )]
                                              )])
+    if hasattr(platform, "python_implementation") and platform.python_implementation() == "PyPy":
+        features = {}
+    else:
+        features = {'codeoptimization': codeoptimization}
     extra = dict(
         namespace_packages=["zope"],
         include_package_data = True,
@@ -56,7 +60,7 @@
         tests_require = [],
         install_requires = ['setuptools'],
         extras_require={'docs': ['z3c.recipe.sphinxdoc']},
-        features = {'codeoptimization': codeoptimization}
+        features = features
         )
 
 def read(*rnames):