Hi, I have the same problem with an Argus KVM switch. The mouse stopped atfer the first click to work. uname -a Linux sysiphus 5.8.0-2-amd64 #1 SMP Debian 5.8.10-1 (2020-09-19) x86_64 GNU/Linux Debian Sid ❯ lsusb Bus 004 Device 001: ID 1d6b:0003 Linux Foundation 3.0 root hub Bus 003 Device 004: ID 046d:c245 Logitech, Inc. G400 Optical Mouse Bus 003 Device 003: ID 046d:c326 Logitech, Inc. Washable Keyboard K310 Bus 003 Device 002: ID 1a86:8072 QinHeng Electronics Bus 003 Device 001: ID 1d6b:0002 Linux Foundation 2.0 root hub Bus 002 Device 001: ID 1d6b:0003 Linux Foundation 3.0 root hub Bus 001 Device 001: ID 1d6b:0002 Linux Foundation 2.0 root hub journald Okt 07 19:29:43 sysiphus kernel: usb 3-2: USB disconnect, device number 2 Okt 07 19:29:43 sysiphus kernel: usb 3-2.1: USB disconnect, device number 3 Okt 07 19:29:43 sysiphus acpid[587]: input device has been disconnected, fd 5 Okt 07 19:29:43 sysiphus kernel: xhci_hcd 0000:08:00.0: WARN Set TR Deq Ptr cmd failed due to incorrect slot or ep state. Okt 07 19:29:43 sysiphus acpid[587]: input device has been disconnected, fd 6 Okt 07 19:29:43 sysiphus acpid[587]: input device has been disconnected, fd 12 Okt 07 19:29:43 sysiphus kernel: usb 3-2.2: USB disconnect, device number 4 Okt 07 19:29:43 sysiphus kernel: xhci_hcd 0000:08:00.0: WARN Set TR Deq Ptr cmd failed due to incorrect slot or ep state. dmesg with debug [ 2539.095820] xhci_hcd 0000:00:14.0: // Ding dong! [ 2539.095824] xhci_hcd 0000:00:14.0: // Ding dong! [ 2539.095840] xhci_hcd 0000:00:14.0: Slot 17 output ctx = 0x3eac96000 (dma) [ 2539.095841] xhci_hcd 0000:00:14.0: Slot 17 input ctx = 0x3ef030000 (dma) [ 2539.095843] xhci_hcd 0000:00:14.0: Set slot id 17 dcbaa entry 000000003007eed2 to 0x3eac96000 [ 2539.173763] usb 1-10.2: new full-speed USB device number 18 using xhci_hcd [ 2539.173772] xhci_hcd 0000:00:14.0: Set root hub portnum to 10 [ 2539.173775] xhci_hcd 0000:00:14.0: Set fake root hub portnum to 10 [ 2539.173778] xhci_hcd 0000:00:14.0: udev->tt = 000000002e0e39e0 [ 2539.173781] xhci_hcd 0000:00:14.0: udev->ttport = 0xa [ 2539.173789] xhci_hcd 0000:00:14.0: // Ding dong! [ 2539.174915] xhci_hcd 0000:00:14.0: Successful setup address command [ 2539.174922] xhci_hcd 0000:00:14.0: Op regs DCBAA ptr = 0x000003ead2c000 [ 2539.174928] xhci_hcd 0000:00:14.0: Slot ID 17 dcbaa entry @000000003007eed2 = 0x000003eac96000 [ 2539.174933] xhci_hcd 0000:00:14.0: Output Context DMA address = 0x3eac96000 [ 2539.174937] xhci_hcd 0000:00:14.0: Internal device address = 17 [ 2539.198845] xhci_hcd 0000:00:14.0: Max Packet Size for ep 0 changed. [ 2539.198851] xhci_hcd 0000:00:14.0: Max packet size in usb_device = 8 [ 2539.198854] xhci_hcd 0000:00:14.0: Max packet size in xHCI HW = 64 [ 2539.198857] xhci_hcd 0000:00:14.0: Issuing evaluate context command. [ 2539.198867] xhci_hcd 0000:00:14.0: // Ding dong! [ 2539.198886] xhci_hcd 0000:00:14.0: Successful evaluate context command [ 2539.200465] usb 1-10.2: no configurations [ 2539.200472] usb 1-10.2: can't read configurations, error -22 [ 2539.200634] xhci_hcd 0000:00:14.0: // Ding dong! [ 2539.200641] usb 1-10-port2: unable to enumerate USB device https://www.sendspace.com/file/d923jl trace file All other kernel parameters above I have tested without success. Micha