diff -Nru distro-info-1.1build1/debian/changelog distro-info-1.1ubuntu0.1/debian/changelog
--- distro-info-1.1build1/debian/changelog	2022-03-23 14:50:40.000000000 +0100
+++ distro-info-1.1ubuntu0.1/debian/changelog	2023-04-25 15:30:42.000000000 +0200
@@ -1,3 +1,9 @@
+distro-info (1.1ubuntu0.1) jammy; urgency=medium
+
+  * python: Use PEP440 compliant version in setup.py (LP: #1991606)
+
+ -- Benjamin Drung <bdrung@ubuntu.com>  Tue, 25 Apr 2023 15:30:42 +0200
+
 distro-info (1.1build1) jammy; urgency=medium
 
   * No-change rebuild for ppc64el baseline bump.
diff -Nru distro-info-1.1build1/debian/control distro-info-1.1ubuntu0.1/debian/control
--- distro-info-1.1build1/debian/control	2021-11-04 22:27:37.000000000 +0100
+++ distro-info-1.1ubuntu0.1/debian/control	2023-04-25 15:30:42.000000000 +0200
@@ -1,7 +1,8 @@
 Source: distro-info
 Section: devel
 Priority: optional
-Maintainer: Benjamin Drung <bdrung@debian.org>
+Maintainer: Ubuntu Developers <ubuntu-devel-discuss@lists.ubuntu.com>
+XSBC-Original-Maintainer: Benjamin Drung <bdrung@debian.org>
 Uploaders: Stefano Rivera <stefanor@debian.org>
 Build-Depends: debhelper-compat (= 13),
                dh-python,
diff -Nru distro-info-1.1build1/python/distro_info_test/test_setup.py distro-info-1.1ubuntu0.1/python/distro_info_test/test_setup.py
--- distro-info-1.1build1/python/distro_info_test/test_setup.py	1970-01-01 01:00:00.000000000 +0100
+++ distro-info-1.1ubuntu0.1/python/distro_info_test/test_setup.py	2023-04-25 15:30:05.000000000 +0200
@@ -0,0 +1,58 @@
+# Copyright (C) 2022, Benjamin Drung <bdrung@debian.org>
+#
+# Permission to use, copy, modify, and/or distribute this software for any
+# purpose with or without fee is hereby granted, provided that the above
+# copyright notice and this permission notice appear in all copies.
+#
+# THE SOFTWARE IS PROVIDED "AS IS" AND THE AUTHOR DISCLAIMS ALL WARRANTIES WITH
+# REGARD TO THIS SOFTWARE INCLUDING ALL IMPLIED WARRANTIES OF MERCHANTABILITY
+# AND FITNESS. IN NO EVENT SHALL THE AUTHOR BE LIABLE FOR ANY SPECIAL, DIRECT,
+# INDIRECT, OR CONSEQUENTIAL DAMAGES OR ANY DAMAGES WHATSOEVER RESULTING FROM
+# LOSS OF USE, DATA OR PROFITS, WHETHER IN AN ACTION OF CONTRACT, NEGLIGENCE OR
+# OTHER TORTIOUS ACTION, ARISING OUT OF OR IN CONNECTION WITH THE USE OR
+# PERFORMANCE OF THIS SOFTWARE.
+
+"""Test functions in setup.py."""
+
+import unittest
+import unittest.mock
+
+from setup import make_pep440_compliant
+
+
+class SetupTestCase(unittest.TestCase):
+    """Test functions in setup.py."""
+
+    def test_make_pep440_compliant_unchanged(self) -> None:
+        """Test make_pep440_compliant() with already correct version."""
+        self.assertEqual(make_pep440_compliant("1.2"), "1.2")
+
+    def test_make_pep440_compliant_debian_backport(self) -> None:
+        """Test make_pep440_compliant() with Debian backport version."""
+        self.assertEqual(make_pep440_compliant("0.21~bpo9+1"), "0.21+bpo9.1")
+
+    def test_make_pep440_compliant_debian_stable(self) -> None:
+        """Test make_pep440_compliant() with Debian stable update."""
+        self.assertEqual(make_pep440_compliant("2.21.3+deb11u1"), "2.21.3+deb11u1")
+
+    def test_make_pep440_compliant_debian_stable_backport(self) -> None:
+        """Test make_pep440_compliant() with Debian stable backport."""
+        self.assertEqual(make_pep440_compliant("2.21.3+deb11u1~bpo10+1"), "2.21.3+deb11u1.bpo10.1")
+
+    def test_make_pep440_compliant_tilde(self) -> None:
+        """Test make_pep440_compliant() with tilde in Debian version."""
+        self.assertEqual(make_pep440_compliant("0.175~18.04.3"), "0.175+18.04.3")
+
+    def test_make_pep440_compliant_ubuntu(self) -> None:
+        """Test make_pep440_compliant() with Ubuntu version."""
+        self.assertEqual(make_pep440_compliant("1.1ubuntu1"), "1.1+ubuntu1")
+
+    def test_make_pep440_compliant_ubuntu_backport(self) -> None:
+        """Test make_pep440_compliant() with Ubuntu backport version."""
+        self.assertEqual(
+            make_pep440_compliant("2.22.1ubuntu1~bpo20.04.1"), "2.22.1+ubuntu1.bpo20.04.1"
+        )
+
+    def test_make_pep440_compliant_ubuntu_security(self) -> None:
+        """Test make_pep440_compliant() with Ubuntu security update."""
+        self.assertEqual(make_pep440_compliant("2.17.12ubuntu1.1"), "2.17.12+ubuntu1.1")
diff -Nru distro-info-1.1build1/python/setup.py distro-info-1.1ubuntu0.1/python/setup.py
--- distro-info-1.1build1/python/setup.py	2021-11-04 22:27:37.000000000 +0100
+++ distro-info-1.1ubuntu0.1/python/setup.py	2023-04-25 15:30:05.000000000 +0200
@@ -24,10 +24,22 @@
     return version
 
 
+def make_pep440_compliant(version: str) -> str:
+    """Convert the version into a PEP440 compliant version."""
+    public_version_re = re.compile(r"^([0-9][0-9.]*(?:(?:a|b|rc|.post|.dev)[0-9]+)*)\+?")
+    _, public, local = public_version_re.split(version, maxsplit=1)
+    if not local:
+        return version
+    sanitized_local = re.sub("[+~]+", ".", local).strip(".")
+    pep440_version = f"{public}+{sanitized_local}"
+    assert re.match("^[a-zA-Z0-9.]+$", sanitized_local), f"'{pep440_version}' not PEP440 compliant"
+    return pep440_version
+
+
 if __name__ == "__main__":
     setup(
         name="distro-info",
-        version=get_debian_version(),
+        version=make_pep440_compliant(get_debian_version()),
         py_modules=PY_MODULES,
         packages=PACKAGES,
         test_suite="distro_info_test",