What I am seeing today on both 32-bit and 64-bit ISOs for AA (20170511) is that the checkboxes can be freely selected or deselected until the options dialog is closed. On reopening, the checkboxes are "locked". They cannot be selected or deselected until the panel is restarted, normal operation resumes until the dialog is closed again.
I think you should be able to change your mind without having to restart the panel before you can make further changes.
What I am seeing today on both 32-bit and 64-bit ISOs for AA (20170511) is that the checkboxes can be freely selected or deselected until the options dialog is closed. On reopening, the checkboxes are "locked". They cannot be selected or deselected until the panel is restarted, normal operation resumes until the dialog is closed again.
I think you should be able to change your mind without having to restart the panel before you can make further changes.