Ultimately, things got so bad that I wiped it and re-installed.  It was locking up, fsck would fail, updates wouldn't install.  Something had just gone horribly wrong.  I've not had much luck with this version of Ubuntu, but as always, thanks for responding to my plea for help.  Perhaps install number 38 will be the magic number...

On Tue, May 6, 2008 at 8:20 AM, Michael Vogt <michael.vogt@ubuntu.com> wrote:
Thanks for your bugreport.

This sounds like the lists file is/was corrupted at some point. Could you please open a terminal and run:
$ sudo rm /var/lib/apt/lists/us*
$ sudo apt-get update
and see if that fixes the problem?

** Changed in: update-manager (Ubuntu)
      Status: New => Incomplete

--
Could not initialize the package information
https://bugs.launchpad.net/bugs/225830
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--
Frank Hieber

Mac OS X...because making UNIX user-friendly was easier than fixing Windows.