Same here, 
Feb  4 08:06:56 755OTP compiz[2604]: extern "Python": function Cryptography_rand_status() called, but @ffi.def_extern() was not called in the current subinterpreter.  Returning 0.
Kodi and Ubuntu 16.10

$ lsb_release -a; uname -a; grep -r ppa /etc/apt/*
No LSB modules are available.
Distributor ID:	Ubuntu
Description:	Ubuntu 16.10
Release:	16.10
Codename:	yakkety
Linux 755OTP 4.8.0-37-generic #39-Ubuntu SMP Thu Jan 26 02:27:07 UTC 2017 x86_64 x86_64 x86_64 GNU/Linux
/etc/apt/sources.list.d/stebbins-ubuntu-handbrake-releases-wily.list.distUpgrade:# deb http://ppa.launchpad.net/stebbins/handbrake-releases/ubuntu xenial main # забранен при надграждане до xenial
/etc/apt/sources.list.d/stebbins-ubuntu-handbrake-releases-wily.list.distUpgrade:# deb-src http://ppa.launchpad.net/stebbins/handbrake-releases/ubuntu wily main
/etc/apt/sources.list.d/stebbins-ubuntu-handbrake-releases-wily.list:# deb http://ppa.launchpad.net/stebbins/handbrake-releases/ubuntu xenial main # забранен при надграждане до xenial
/etc/apt/sources.list.d/stebbins-ubuntu-handbrake-releases-wily.list:# deb-src http://ppa.launchpad.net/stebbins/handbrake-releases/ubuntu wily main
/etc/apt/sources.list.d/graphics-drivers-ubuntu-ppa-yakkety.list:deb http://ppa.launchpad.net/graphics-drivers/ppa/ubuntu yakkety main
/etc/apt/sources.list.d/graphics-drivers-ubuntu-ppa-yakkety.list:# deb-src http://ppa.launchpad.net/graphics-drivers/ppa/ubuntu yakkety main
/etc/apt/sources.list.d/team-xbmc-ubuntu-ppa-xenial.list.distUpgrade:# deb-src http://ppa.launchpad.net/team-xbmc/ppa/ubuntu xenial main
/etc/apt/sources.list.d/team-xbmc-ubuntu-ppa-wily.list:# deb-src http://ppa.launchpad.net/team-xbmc/ppa/ubuntu wily main
/etc/apt/sources.list.d/stebbins-ubuntu-handbrake-releases-wily.list.save:# deb http://ppa.launchpad.net/stebbins/handbrake-releases/ubuntu xenial main # забранен при надграждане до xenial
/etc/apt/sources.list.d/stebbins-ubuntu-handbrake-releases-wily.list.save:# deb-src http://ppa.launchpad.net/stebbins/handbrake-releases/ubuntu wily main
/etc/apt/sources.list.d/team-xbmc-ubuntu-ppa-wily.list.distUpgrade:# deb-src http://ppa.launchpad.net/team-xbmc/ppa/ubuntu wily main
/etc/apt/sources.list.d/graphics-drivers-ubuntu-ppa-yakkety.list.save:deb http://ppa.launchpad.net/graphics-drivers/ppa/ubuntu yakkety main
/etc/apt/sources.list.d/graphics-drivers-ubuntu-ppa-yakkety.list.save:# deb-src http://ppa.launchpad.net/graphics-drivers/ppa/ubuntu yakkety main
/etc/apt/sources.list.d/team-xbmc-ubuntu-ppa-vivid.list.distUpgrade:# deb http://ppa.launchpad.net/team-xbmc/ppa/ubuntu yakkety main # забранен при надграждане до wily забранен при надграждане до xenial забранен при надграждане до yakkety
/etc/apt/sources.list.d/team-xbmc-ubuntu-ppa-vivid.list.distUpgrade:# deb-src http://ppa.launchpad.net/team-xbmc/ppa/ubuntu vivid main
/etc/apt/sources.list.d/team-xbmc-ubuntu-ppa-wily.list.save:# deb-src http://ppa.launchpad.net/team-xbmc/ppa/ubuntu wily main
/etc/apt/sources.list.d/team-xbmc-ubuntu-ppa-vivid.list:deb http://ppa.launchpad.net/team-xbmc/ppa/ubuntu yakkety main # забранен при надграждане до wily забранен при надграждане до xenial забранен при надграждане до yakkety
/etc/apt/sources.list.d/team-xbmc-ubuntu-ppa-vivid.list:# deb-src http://ppa.launchpad.net/team-xbmc/ppa/ubuntu vivid main
/etc/apt/sources.list.d/team-xbmc-ubuntu-ppa-yakkety.list:# deb-src http://ppa.launchpad.net/team-xbmc/ppa/ubuntu yakkety main
/etc/apt/sources.list.d/team-xbmc-ubuntu-ppa-xenial.list:# deb-src http://ppa.launchpad.net/team-xbmc/ppa/ubuntu xenial main
/etc/apt/sources.list.d/team-xbmc-ubuntu-ppa-xenial.list.save:# deb-src http://ppa.launchpad.net/team-xbmc/ppa/ubuntu xenial main
/etc/apt/sources.list.d/team-xbmc-ubuntu-ppa-vivid.list.save:# deb http://ppa.launchpad.net/team-xbmc/ppa/ubuntu yakkety main # забранен при надграждане до wily забранен при надграждане до xenial забранен при надграждане до yakkety
/etc/apt/sources.list.d/team-xbmc-ubuntu-ppa-vivid.list.save:# deb-src http://ppa.launchpad.net/team-xbmc/ppa/ubuntu vivid main
Kodi is from ppa, I run Kodi in fulscreen, if I log into Kodi session - no problem, with Unity session problem exist. I will try with gnome shell session.