So I have been doing more research and I think Im narrowing it down now. In summary I think: After a period of no network use, ACPI thinks IRQ 23 isnt needed ACPI turns off IRQ 23 eth0 times out and wont come back without reboot ifdown/ifup wont fix it Jun 21 03:04:07 ppp kernel: [ 57.447218] eth0: no IPv6 routers present Jun 21 04:29:46 ppp kernel: [ 5193.747505] irq 23: nobody cared (try booting with the "irqpoll" option) Jun 21 04:29:46 ppp kernel: [ 5193.747514] Pid: 0, comm: swapper Tainted: P 2.6.24-19-generic #1 Jun 21 04:29:46 ppp kernel: [ 5193.747516] Jun 21 04:29:46 ppp kernel: [ 5193.747517] Call Trace: Jun 21 04:29:46 ppp kernel: [ 5193.747519] [__report_bad_irq+0x1e/0x80] __report_bad_irq+0x1e/0x80 Jun 21 04:29:46 ppp kernel: [ 5193.747550] [note_interrupt+0x2ad/0x2e0] note_interrupt+0x2ad/0x2e0 Jun 21 04:29:46 ppp kernel: [ 5193.747562] [handle_fasteoi_irq+0xa1/0x110] handle_fasteoi_irq+0xa1/0x110 Jun 21 04:29:46 ppp kernel: [ 5193.747571] [do_IRQ+0x7b/0x100] do_IRQ+0x7b/0x100 Jun 21 04:29:46 ppp kernel: [ 5193.747577] [ret_from_intr+0x0/0x0a] ret_from_intr+0x0/0xa Jun 21 04:29:46 ppp kernel: [ 5193.747583] [pci_conf1_read+0x0/0x100] pci_conf1_read+0x0/0x100 Jun 21 04:29:46 ppp kernel: [ 5193.747596] [__do_softirq+0x60/0xe0] __do_softirq+0x60/0xe0 Jun 21 04:29:46 ppp kernel: [ 5193.747609] [call_softirq+0x1c/0x30] call_softirq+0x1c/0x30 Jun 21 04:29:46 ppp kernel: [ 5193.747614] [do_softirq+0x35/0x90] do_softirq+0x35/0x90 Jun 21 04:29:46 ppp kernel: [ 5193.747618] [irq_exit+0x88/0x90] irq_exit+0x88/0x90 Jun 21 04:29:46 ppp kernel: [ 5193.747621] [do_IRQ+0x80/0x100] do_IRQ+0x80/0x100 Jun 21 04:29:46 ppp kernel: [ 5193.747624] [default_idle+0x0/0x40] default_idle+0x0/0x40 Jun 21 04:29:46 ppp kernel: [ 5193.747628] [default_idle+0x0/0x40] default_idle+0x0/0x40 Jun 21 04:29:46 ppp kernel: [ 5193.747630] [ret_from_intr+0x0/0x0a] ret_from_intr+0x0/0xa Jun 21 04:29:46 ppp kernel: [ 5193.747633] [lapic_next_event+0x0/0x10] lapic_next_event+0x0/0x10 Jun 21 04:29:46 ppp kernel: [ 5193.747648] [default_idle+0x29/0x40] default_idle+0x29/0x40 Jun 21 04:29:46 ppp kernel: [ 5193.747654] [cpu_idle+0x6f/0xc0] cpu_idle+0x6f/0xc0 Jun 21 04:29:46 ppp kernel: [ 5193.747662] [start_kernel+0x2c5/0x350] start_kernel+0x2c5/0x350 Jun 21 04:29:46 ppp kernel: [ 5193.747670] [x86_64_start_kernel+0x12e/0x140] _sinittext+0x12e/0x140 Jun 21 04:29:46 ppp kernel: [ 5193.747678] Jun 21 04:29:46 ppp kernel: [ 5193.747679] handlers: Jun 21 04:29:46 ppp kernel: [ 5193.747680] [usbcore:usb_hcd_irq+0x0/0x60] (usb_hcd_irq+0x0/0x60 [usbcore]) Jun 21 04:29:46 ppp kernel: [ 5193.747702] [via_rhine:rhine_interrupt+0x0/0x7f0] (rhine_interrupt+0x0/0x7f0 [via_rhine]) Jun 21 04:29:46 ppp kernel: [ 5193.747710] Disabling IRQ #23 Jun 21 04:34:46 ppp kernel: [ 5493.104588] NETDEV WATCHDOG: eth0: transmit timed out Jun 21 04:34:46 ppp kernel: [ 5493.104738] eth0: Transmit timed out, status 0003, PHY status 786d, resetting... Jun 21 04:34:46 ppp kernel: [ 5493.105384] eth0: link up, 100Mbps, full-duplex, lpa 0x45E1 Jun 21 05:05:02 ppp kernel: [ 7308.203455] NETDEV WATCHDOG: eth0: transmit timed out Jun 21 05:05:02 ppp kernel: [ 7308.203606] eth0: Transmit timed out, status 1003, PHY status 786d, resetting... Jun 21 05:05:02 ppp kernel: [ 7308.204254] eth0: link up, 100Mbps, full-duplex, lpa 0x45E1 Jun 21 05:35:16 ppp kernel: [ 9121.303308] NETDEV WATCHDOG: eth0: transmit timed out Jun 21 05:35:16 ppp kernel: [ 9121.303457] eth0: Transmit timed out, status 1003, PHY status 786d, resetting... Jun 21 05:35:16 ppp kernel: [ 9121.304106] eth0: link up, 100Mbps, full-duplex, lpa 0x45E1 Jun 21 06:05:32 ppp kernel: [10936.402170] NETDEV WATCHDOG: eth0: transmit timed out Jun 21 06:05:32 ppp kernel: [10936.402319] eth0: Transmit timed out, status 0003, PHY status 786d, resetting... Jun 21 06:05:32 ppp kernel: [10936.402968] eth0: link up, 100Mbps, full-duplex, lpa 0x45E1 Jun 21 06:12:40 ppp kernel: [11364.189787] NETDEV WATCHDOG: eth0: transmit timed out Jun 21 06:12:40 ppp kernel: [11364.189937] eth0: Transmit timed out, status 0003, PHY status 786d, resetting... Jun 21 06:12:40 ppp kernel: [11364.190589] eth0: link up, 100Mbps, full-duplex, lpa 0x45E1 Jun 21 06:36:06 ppp kernel: [12769.492097] NETDEV WATCHDOG: eth0: transmit timed out Jun 21 06:36:06 ppp kernel: [12769.492247] eth0: Transmit timed out, status 0003, PHY status 786d, resetting... Jun 21 06:36:06 ppp kernel: [12769.492892] eth0: link up, 100Mbps, full-duplex, lpa 0x45E1 Jun 21 07:06:22 ppp kernel: [14584.590959] NETDEV WATCHDOG: eth0: transmit timed out Jun 21 07:06:22 ppp kernel: [14584.591109] eth0: Transmit timed out, status 0003, PHY status 786d, resetting... Jun 21 07:06:22 ppp kernel: [14584.591757] eth0: link up, 100Mbps, full-duplex, lpa 0x45E1 Jun 21 07:36:36 ppp kernel: [16397.690817] NETDEV WATCHDOG: eth0: transmit timed out Jun 21 07:36:36 ppp kernel: [16397.690967] eth0: Transmit timed out, status 0003, PHY status 786d, resetting... Jun 21 07:36:36 ppp kernel: [16397.691615] eth0: link up, 100Mbps, full-duplex, lpa 0x45E1 Jun 21 08:06:54 ppp kernel: [18214.788695] NETDEV WATCHDOG: eth0: transmit timed out Jun 21 08:06:54 ppp kernel: [18214.788846] eth0: Transmit timed out, status 0003, PHY status 786d, resetting... Jun 21 08:06:54 ppp kernel: [18214.789492] eth0: link up, 100Mbps, full-duplex, lpa 0x45E1