I experienced the same issue with  Ryzen 5 1600 and Ryzen 7 1700, with AsRock AB350M PRO4 and Asus Prime B350M-A.
I try with ubuntu 16.04 normal and hwe kernel, and ubuntu 17.10.

On the system with Asus motherboard, I found a detailed log:
Dec 19 06:25:04 am02 kernel: [227622.995187] NMI watchdog: BUG: soft lockup - CPU#0 stuck for 22s! [kworker/0:1:115]
Dec 19 06:25:04 am02 kernel: [227622.996201] Modules linked in: xt_CHECKSUM iptable_mangle ipt_MASQUERADE nf_nat_masquerade_ipv4 iptable_nat nf_nat_ipv4 nf_nat nf_conntrack_ipv4 nf_defrag_ipv4 xt_conntrack nf_conntrack ipt_REJECT nf_reject_ipv4 xt_tcpudp bridge stp llc ebtable_filter ebtables ip6table_filter ip6_tables iptable_filter ip_tables x_tables snd_hda_codec_hdmi nls_iso8859_1 eeepc_wmi asus_wmi sparse_keymap edac_mce_amd edac_core snd_hda_intel snd_hda_codec snd_hda_core snd_hwdep snd_pcm snd_timer i2c_piix4 snd ccp soundcore mac_hid 8250_dw i2c_designware_platform i2c_designware_core shpchp kvm_amd kvm irqbypass ib_iser rdma_cm iw_cm ib_cm ib_core configfs iscsi_tcp libiscsi_tcp libiscsi scsi_transport_iscsi autofs4 btrfs raid10 raid456 async_raid6_recov async_memcpy async_pq async_xor async_tx xor raid6_pq libcrc32c raid1
Dec 19 06:25:04 am02 kernel: [227622.996242]  raid0 multipath linear nouveau crct10dif_pclmul crc32_pclmul ghash_clmulni_intel pcbc mxm_wmi video i2c_algo_bit ttm aesni_intel drm_kms_helper aes_x86_64 crypto_simd syscopyarea glue_helper sysfillrect cryptd sysimgblt fb_sys_fops drm r8169 ahci mii libahci wmi fjes gpio_amdpt gpio_generic
Dec 19 06:25:04 am02 kernel: [227622.996263] CPU: 0 PID: 115 Comm: kworker/0:1 Tainted: G             L  4.10.0-28-generic #32~16.04.2-Ubuntu
Dec 19 06:25:04 am02 kernel: [227622.996264] Hardware name: System manufacturer System Product Name/PRIME B350M-A, BIOS 0611 05/05/2017
Dec 19 06:25:04 am02 kernel: [227622.996271] Workqueue: events netstamp_clear
Dec 19 06:25:04 am02 kernel: [227622.996274] task: ffff9d12fa288000 task.stack: ffffba804361c000
Dec 19 06:25:04 am02 kernel: [227622.996278] RIP: 0010:smp_call_function_many+0x1f1/0x250
Dec 19 06:25:04 am02 kernel: [227622.996280] RSP: 0018:ffffba804361fce8 EFLAGS: 00000202 ORIG_RAX: ffffffffffffff10
Dec 19 06:25:04 am02 kernel: [227622.996283] RAX: 0000000000000003 RBX: 0000000000000010 RCX: 000000000000000c
Dec 19 06:25:04 am02 kernel: [227622.996285] RDX: ffff9d12fe91d0f8 RSI: 0000000000000010 RDI: ffff9d12fe021d30
Dec 19 06:25:04 am02 kernel: [227622.996286] RBP: ffffba804361fd20 R08: 0000000000000000 R09: 000000000000fffe
Dec 19 06:25:04 am02 kernel: [227622.996287] R10: ffffeceadfd69100 R11: ffff9d12fe021d30 R12: ffffffffbb634c60
Dec 19 06:25:04 am02 kernel: [227622.996288] R13: 0000000000000000 R14: ffff9d12fe61a340 R15: 000000000001a300
Dec 19 06:25:04 am02 kernel: [227622.996291] FS:  0000000000000000(0000) GS:ffff9d12fe600000(0000) knlGS:0000000000000000
Dec 19 06:25:04 am02 kernel: [227622.996292] CS:  0010 DS: 0000 ES: 0000 CR0: 0000000080050033
Dec 19 06:25:04 am02 kernel: [227622.996294] CR2: 00007f5780200a58 CR3: 00000007f67ca000 CR4: 00000000003406f0
Dec 19 06:25:04 am02 kernel: [227622.996296] Call Trace:
Dec 19 06:25:04 am02 kernel: [227622.996301]  ? netif_receive_skb_internal+0x20/0xa0
Dec 19 06:25:04 am02 kernel: [227622.996304]  ? arch_unregister_cpu+0x30/0x30
Dec 19 06:25:04 am02 kernel: [227622.996307]  ? netif_receive_skb_internal+0x21/0xa0
Dec 19 06:25:04 am02 kernel: [227622.996309]  on_each_cpu+0x2d/0x60
Dec 19 06:25:04 am02 kernel: [227622.996312]  ? netif_receive_skb_internal+0x20/0xa0
Dec 19 06:25:04 am02 kernel: [227622.996314]  text_poke_bp+0x6a/0xf0
Dec 19 06:25:04 am02 kernel: [227622.996316]  ? netif_receive_skb_internal+0x20/0xa0
Dec 19 06:25:04 am02 kernel: [227622.996318]  arch_jump_label_transform+0x9b/0x120
Dec 19 06:25:04 am02 kernel: [227622.996322]  __jump_label_update+0x76/0x90
Dec 19 06:25:04 am02 kernel: [227622.996324]  jump_label_update+0x88/0x90
Dec 19 06:25:04 am02 kernel: [227622.996326]  static_key_slow_inc+0x95/0xa0
Dec 19 06:25:04 am02 kernel: [227622.996328]  static_key_enable+0x1d/0x50
Dec 19 06:25:04 am02 kernel: [227622.996330]  netstamp_clear+0x2d/0x40
Dec 19 06:25:04 am02 kernel: [227622.996333]  process_one_work+0x16b/0x4a0
Dec 19 06:25:04 am02 kernel: [227622.996335]  worker_thread+0x4b/0x500
Dec 19 06:25:04 am02 kernel: [227622.996339]  kthread+0x109/0x140
Dec 19 06:25:04 am02 kernel: [227622.996341]  ? process_one_work+0x4a0/0x4a0
Dec 19 06:25:04 am02 kernel: [227622.996344]  ? kthread_create_on_node+0x60/0x60
Dec 19 06:25:04 am02 kernel: [227622.996347]  ret_from_fork+0x2c/0x40
Dec 19 06:25:04 am02 kernel: [227622.996348] Code: 63 d2 e8 f3 da 34 00 3b 05 c1 1e e8 00 89 c1 0f 8d 9a fe ff ff 48 98 49 8b 16 48 03 14 c5 e0 73 34 bc 8b 42 18 a8 01 74 09 f3 90 <8b> 42 18 a8 01 75 f7 eb bd 0f b6 4d d0 4c 89 ea 4c 89 e6 44 89
Dec 19 06:25:32 am02 kernel: [227650.996992] NMI watchdog: BUG: soft lockup - CPU#0 stuck for 22s! [kworker/0:1:115]

If I can help, I can give SSH access for my systems.