This certainly looks like a kernel bug or hardware failure. Your errors coming from the 'pcieport' kernel module appear to correlate with errors from the 'nvme' module (for a solid state hard drive). So I think that's the problem area, which will indeed slow down everything and make various hardware devices non-responsive.
Your description also mentions wifi issues (which would be your 'ath10k_pci' kernel module) but I think that's most likely a side-effect of the PCIe problems from the former.
If I had to guess then you probably need one of:
(a) a kernel bug fix; or
(b) a new solid state drive; or
(c) a new motherboard.
Thanks.
This certainly looks like a kernel bug or hardware failure. Your errors coming from the 'pcieport' kernel module appear to correlate with errors from the 'nvme' module (for a solid state hard drive). So I think that's the problem area, which will indeed slow down everything and make various hardware devices non-responsive.
Your description also mentions wifi issues (which would be your 'ath10k_pci' kernel module) but I think that's most likely a side-effect of the PCIe problems from the former.
If I had to guess then you probably need one of:
(a) a kernel bug fix; or
(b) a new solid state drive; or
(c) a new motherboard.
We'll wait and see what the kernel people say...