We've encountered this as well with 5.6.26-74.0-1.trusty. This Percona was configured as slave. We've also seen the errors on standalone instances with the same version. In all cases a rollback to version 5.6.25-73.1-1.trusty solved the problem (Percona starts without problems). The errors after the upgrade: Normal shutdown after package upgrade (5.6.25-73.1-1.trusty -> 5.6.26-74.0-1.trusty): 2015-09-24 04:36:01 2849 [Note] Giving 6 client threads a chance to die gracefully 2015-09-24 04:36:01 2849 [Note] Event Scheduler: Purging the queue. 0 events 2015-09-24 04:36:01 2849 [Note] Shutting down slave threads 2015-09-24 04:36:01 2849 [Note] Error reading relay log event: slave SQL thread was killed 2015-09-24 04:36:01 2849 [ERROR] Error reading packet from server: Lost connection to MySQL server during query ( server_errno=2013) 2015-09-24 04:36:01 2849 [Note] Slave I/O thread killed while reading event 2015-09-24 04:36:01 2849 [Note] Slave I/O thread exiting, read up to log 'binlog.000891', position 670357433 2015-09-24 04:36:11 2849 [Note] Forcefully disconnecting 1 remaining clients 2015-09-24 04:36:11 2849 [Warning] /usr/sbin/mysqld: Forcing close of thread 1928716 user: 'level23' 2015-09-24 04:36:11 2849 [Note] Binlog end 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'partition' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'PERFORMANCE_SCHEMA' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'ARCHIVE' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'BLACKHOLE' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'INNODB_CHANGED_PAGES' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'INNODB_SYS_DATAFILES' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'INNODB_SYS_TABLESPACES' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'INNODB_SYS_FOREIGN_COLS' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'INNODB_SYS_FOREIGN' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'INNODB_SYS_FIELDS' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'INNODB_SYS_COLUMNS' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'INNODB_SYS_INDEXES' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'INNODB_SYS_TABLESTATS' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'INNODB_SYS_TABLES' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'INNODB_FT_INDEX_TABLE' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'INNODB_FT_INDEX_CACHE' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'INNODB_FT_CONFIG' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'INNODB_FT_BEING_DELETED' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'INNODB_FT_DELETED' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'INNODB_FT_DEFAULT_STOPWORD' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'INNODB_METRICS' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'INNODB_BUFFER_POOL_STATS' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'INNODB_BUFFER_PAGE_LRU' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'INNODB_BUFFER_PAGE' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'INNODB_CMP_PER_INDEX_RESET' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'INNODB_CMP_PER_INDEX' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'INNODB_CMPMEM_RESET' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'INNODB_CMPMEM' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'INNODB_CMP_RESET' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'INNODB_CMP' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'INNODB_LOCK_WAITS' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'INNODB_LOCKS' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'INNODB_TRX' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'XTRADB_RSEG' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'XTRADB_INTERNAL_HASH_TABLES' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'XTRADB_READ_VIEW' 2015-09-24 04:36:11 2849 [Note] Shutting down plugin 'InnoDB' 2015-09-24 04:36:11 2849 [Note] InnoDB: FTS optimize thread exiting. 2015-09-24 04:36:11 2849 [Note] InnoDB: Starting shutdown... 2015-09-24 04:36:11 7ef8b7ff8700 InnoDB: Dumping buffer pool(s) to .//ib_buffer_pool 2015-09-24 04:36:12 7ef8b7ff8700 InnoDB: Buffer pool(s) dump completed at 150924 4:36:12 2015-09-24 04:36:18 2849 [Note] InnoDB: Shutdown completed; log sequence number 6657364619218 2015-09-24 04:36:18 2849 [Note] Shutting down plugin 'MyISAM' 2015-09-24 04:36:18 2849 [Note] Shutting down plugin 'MRG_MYISAM' 2015-09-24 04:36:18 2849 [Note] Shutting down plugin 'CSV' 2015-09-24 04:36:18 2849 [Note] Shutting down plugin 'MEMORY' 2015-09-24 04:36:18 2849 [Note] Shutting down plugin 'sha256_password' 2015-09-24 04:36:18 2849 [Note] Shutting down plugin 'mysql_old_password' 2015-09-24 04:36:18 2849 [Note] Shutting down plugin 'mysql_native_password' 2015-09-24 04:36:18 2849 [Note] Shutting down plugin 'binlog' 2015-09-24 04:36:18 2849 [Note] /usr/sbin/mysqld: Shutdown complete Startup with 5.6.26-74.0-1.trusty 150924 04:36:18 mysqld_safe mysqld from pid file /var/run/mysqld/mysqld.pid ended 2015-09-24 04:36:26 7f858316b780 InnoDB: Warning: Using innodb_additional_mem_pool_size is DEPRECATED. This option may be removed in future releases, together with the option innodb_use_sys_malloc and with the InnoDB's internal memory allocator. 2015-09-24 04:36:26 7f858316b780 InnoDB: Warning: Using innodb_locks_unsafe_for_binlog is DEPRECATED. This option may be removed in future releases. Please use READ COMMITTED transaction isolation level instead, see http://dev.mysql.com/doc/refman/5.6/en/set-transaction.html. 2015-09-24 04:36:26 24729 [Note] InnoDB: Using atomics to ref count buffer pool pages 2015-09-24 04:36:26 24729 [Note] InnoDB: The InnoDB memory heap is disabled 2015-09-24 04:36:26 24729 [Note] InnoDB: Mutexes and rw_locks use GCC atomic builtins 2015-09-24 04:36:26 24729 [Note] InnoDB: Memory barrier is not used 2015-09-24 04:36:26 24729 [Note] InnoDB: Compressed tables use zlib 1.2.8 2015-09-24 04:36:26 24729 [Note] InnoDB: Using Linux native AIO 2015-09-24 04:36:26 24729 [Note] InnoDB: Using CPU crc32 instructions 2015-09-24 04:36:26 24729 [Note] InnoDB: Initializing buffer pool, size = 40.0G 2015-09-24 04:36:29 24729 [Note] InnoDB: Completed initialization of buffer pool 2015-09-24 04:36:29 24729 [Note] InnoDB: Highest supported file format is Barracuda. 2015-09-24 04:36:29 24729 [Note] InnoDB: starting tracking changed pages from LSN 6657364619218 2015-09-24 04:36:30 24729 [Note] InnoDB: 128 rollback segment(s) are active. 2015-09-24 04:36:30 24729 [Note] InnoDB: Waiting for purge to start 2015-09-24 04:36:30 24729 [Note] InnoDB: Percona XtraDB (http://www.percona.com) 5.6.26-74.0 started; log sequence number 6657364619218 2015-09-24 04:36:30 7f7afcc78700 InnoDB: Loading buffer pool(s) from .//ib_buffer_pool 2015-09-24 04:36:30 24729 [Warning] Bootstrap mode disables GTIDs. Bootstrap mode should only be used by mysql_install_db which initializes the MySQL data directory and creates system tables. 2015-09-24 04:36:30 24729 [Note] RSA private key file not found: /var/lib/mysql//private_key.pem. Some authentication plugins will not work. 2015-09-24 04:36:30 24729 [Note] RSA public key file not found: /var/lib/mysql//public_key.pem. Some authentication plugins will not work. 2015-09-24 04:36:30 24729 [Note] Binlog end 2015-09-24 04:36:30 24729 [Note] InnoDB: FTS optimize thread exiting. 2015-09-24 04:36:30 24729 [Note] InnoDB: Starting shutdown... 2015-09-24 04:36:30 7f7afcc78700 InnoDB: Buffer pool(s) load completed at 150924 4:36:30 (.//ib_buffer_pool was empty) 2015-09-24 04:36:30 7f7afcc78700 InnoDB: Dumping buffer pool(s) to .//ib_buffer_pool 2015-09-24 04:36:30 7f7afcc78700 InnoDB: Buffer pool(s) dump completed at 150924 4:36:30 2015-09-24 04:36:31 7f7ad75fa700 InnoDB: Error: Write to file ./ib_modified_log_1311_6657364619218.xdb failed at offset 0. InnoDB: 4096 bytes should have been written, only 0 were written. InnoDB: Operating system error number 22. InnoDB: Check that your OS and file system support files of this size. InnoDB: Check also that the disk is not full or a disk quota exceeded. InnoDB: Error number 22 means 'Invalid argument'. InnoDB: Some operating system error numbers are described at InnoDB: http://dev.mysql.com/doc/refman/5.6/en/operating-system-error-codes.html 2015-09-24 04:36:31 7f7ad75fa700 InnoDB: Operating system error number 22 in a file operation. InnoDB: Error number 22 means 'Invalid argument'. InnoDB: Some operating system error numbers are described at InnoDB: http://dev.mysql.com/doc/refman/5.6/en/operating-system-error-codes.html