diff --git a/cloudinit/net/__init__.py b/cloudinit/net/__init__.py
index a072a8d6931b..4f5893ecaa80 100644
--- a/cloudinit/net/__init__.py
+++ b/cloudinit/net/__init__.py
@@ -90,6 +90,16 @@ def is_vlan(devname):
     uevent = str(read_sys_net_safe(devname, "uevent"))
     return 'DEVTYPE=vlan' in uevent.splitlines()
 
+def is_hv_nic(devname):
+    path = sys_dev_path(devname, "device/driver")
+    if not os.path.exists(path):
+        return false
+    return os.path.basename(os.readlink(path)) == "hv_netvsc"
+
+
+def is_hv_mac(mac):
+    return mac.find("00:15:5d:") == 0
+
 
 def is_connected(devname):
     # is_connected isn't really as simple as that.  2 is
@@ -404,6 +414,9 @@ def get_interfaces_by_mac():
         # some devices may not have a mac (tun0)
         if not mac:
             continue
+        # on hyper-v skip synthetic NIC with paired VF
+        if is_hv_nic(name) and not is_hv_mac(mac)
+            continue
         if mac in ret:
             raise RuntimeError(
                 "duplicate mac found! both '%s' and '%s' have mac '%s'" %